National Institute of Pharmaceutical Education and Research
Dept. of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India NIPER HYDERABAD

CONTACT INFORMATION


Dr. T. D. Neelima
Assistant Professor
Department of Medicinal Chemistry
NIPER-Hyderabad

E-Mail: neelima@niperhyd.ac.in

BIOGRAPHY

Dr. Neelima Tangellamudi has completed B.Sc and M.Sc from Osmania University, Hyderabad. She obtained her PhD in asymmetric catalysis under the guidance of Late Dr G. Sundararajan from IIT Madras, in 2008. Thereafter, she joined Institute of Life Sciences at University of Hyderabad, for Postdoctoral Studies with Prof. Javed Iqbal (2008 – 2012). In 2013, she was appointed as Junior Research Scientist, in the ICTP center at Dr. Reddy’s Institute of Life Sciences. Then she joined BVRIT as Associate professor and Principal Investigator of DST funded project in the Department of Chemistry (2015-2017). She has expertise in teaching Organic reaction mechanisms, Stereochemistry, Spectral analysis and Organic synthesis.

AWARDS  &  QUALIFICATIONS
  • Assistant Professor (April 2017 – till date), Department of Medicinal Chemistry, NIPER-Hyderabad, India
  • Associate Professor (Jan 2015 – April 2017, Department of Chemistry, BVRIT, Narsapur, Medak, India
  • Junior Research Scientist (Jan 2013- April 2014), Dr. Reddy’s Institute of Life Sciences, University of Hyderabad campus, Hyderabad
  • Postdoctoral Researcher (May 2008- December 2012), Dr. Reddy’s Institute of Life Sciences, University of Hyderabad campus, Hyderabad
  • Lecturer in Chemistry (1994-1997 and 1998-2002), in reputed colleges affiliated to Osmania University, Hyderabd
  • Project Associate (1997- 1998) Indian Institute of Chemical Technology, Hyderabad
  • Ph.D (Jan 2003- April 2008), IIT Madras, Chennai, India
  • M.Sc (1991–1993), Osmania University, Hyderabad, India
  • B.Sc (1988-1991), Osmania University, Hyderabad, India
  • CSIR- NET (2001) in Chemical Sciences, CSIR, India
  • GATE, 123rd All India Rank with 93.12 percentile
  • Member, American Chemical Society


RESEARCH SUMMARY

Her research work is focused on Novel Synthetic methodologies in organic synthesis and C-H activation. One-pot, modular protocols for generation of privileged structural motifs is at the core of the research. Generation of polycarbo/heterocyclics of various kinds for further biological evaluation against diabeties, cancer and microbial infections is a parallel project. The project deals with application of synthetically appealing and promising strategies from aminoacid and vanilloid precursors. Another research focus is on design and development of organocatalysts and transition metal complexes built around the combination of various natural compounds, as green sustainable catalytic systems. Application of such systems with operational simplicity and low toxicity makes it an attractive way to synthesize medicinally relevant complex structures for their use in pharmaceuticals

SOURCE OF FUNDING
  • DST-SERB, Govt of India.
  • Department of Pharmaceuticals, Govt of India.



PUBLICATIONS
  • Neelima. D. Tangellamudi, Babu Varghese and Sundararajan G. Highly efficient resolution of racemic diethanolamine using (-) camphor-10-sulphonic acid. Arkivoc, 2005, xi, 137- 145.
  • Neelima. D. Tangellamudi* and Sundararajan G. Unexpected chemoselectivity of cyclic enones on introducing additional chirality in diethanolamine ligand in catalytic asymmetric Michael addition reactions using heterobimetallics. Journal of Molecular Catalysis A: Chemical, 2009, 314, 71-80
  • Javed Iqbal, Neelima. D. Tangellamudi*, Balakrishna Dulla and Sridhar Balasubramanian. Sequential C-N and C-O bond Formation in Single pot: Synthesis of 2H-benzo[b][1,4]oxazines from 2,5-dihydroxybenzaldehyde and Aminoacid precursors. Organic. Letters 2012, 14, 552-555.
  • Balakrishna Dulla, Neelima D. Tangellamudi,* Sridhar Balasubramanian, Pushkar Kulkarni, Javed Iqbal,,* Oliver Reiser,* and Manojit Pal*. Isovanillin derived N-(un)substituted hydroxylamines possessing ortho-allylic group: valuable precursors to novel bioactive N-heterocycles. Org. Biomol.Chem., 2014, 12, 2552–2558.
  • Neelima. D. Tangellamudi*, Ravi Kumar M and Nikhita G. Silver mediated sp2C−H functionalization/C-N/C-O bond formation: A Novel Highly Efficient Synthesis of 2- substituted Benzoxazoles. Accepted for Special Invited Lecture/ (Academic) and publication scheduled for the ‘Drug Discovery and Therapy World Congress 2014’, to be held from 16th June – 19th June, 2014, at Boston, MA. USA

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