National Institute of Pharmaceutical Education and Research
Dept. of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India NIPER HYDERABAD

CONTACT INFORMATION


Dr. Arifuddin Mohammed,
Assistant Professor,
Department of Medicinal Chemsitry,
NIPER-Hyderabad

BIOGRAPHY

Dr. Mohammed Arifuddin is born in Hyderabad, India on May 29, 1971. After completion of his schooling education he received his B.Sc. with biology, physics and chemistry as main subject from Osmania University, in 1992. He received his M.Sc. degree in chemistry (specialization organic chemistry) in 1995 from Osmania University. Dr. Arif joined the Indian Institute of Chemical Technology, Hyderabad, India as a project assistant under the supervision of Dr. Ahmed Kamal, on DST-Ranbaxy co laboratory project “Synthesis of Anticancer agents”. He received senior research Fellowship award (1998) from CSIR, New Delhi.

He received his Ph.D. degree in Chemistry in January 2003, on the "Development of Methodologies for the Opening of Oxiranes; Regeneration of Carbonyl Compounds and Synthesis of New Podophyllotoxin Congeners as Anticancer Agents".

AWARDS  &  QUALIFICATIONS
  • Ph.D. (Organic Chemistry), 2003, Osmania University. Hyderabad-India.
  • M.Sc. (English Medium), (Organic Chemistry), 1995, First Division, Osmania university, Hyderabad, A. P., India.
  • B.Sc. (Chemistry, Biology), 1992, First Division, Osmania University, Hyderabad, A. P., India.


RESEARCH SUMMARY

Dr. Arif is extensively working into multi-disciplinary research problems in medicinal chemistry ranging from the synthesis of new chemical entities (NCE’s) as potential therapeutic agents (anticancer, antimicrobial etc) and developments of new synthetic methodologies for organic functional group transformation under eco-friendly conditions which are useful in the organic synthesis. He extensively worked on the synthesis of biological active compounds by using conventional as well modern synthetic organic methods.

SOURCE OF FUNDING
  • Department of Pharmaceuticals (DOP), Ministry of chemical & fertilizers, Govt. of India


 

 


PUBLICATIONS
  • Enatioselective ring opening of epoxide with TMSN3 in the presence of  - cyclodextrin: An efficient route to 1, 2-azido alcohols. Ahmed Kamal, M.Arifuddin and Maddamshetty.V.Rao. Tetrahedron Asymmtry, 1999, 10 , 4261.
  • An efficient reduction of azides to amines: Synthesis of DNA interactive pyrrolo [2,1-c] [1,4] benzodiazepines. Ahmed Kamal, E. Laxman and M. Arifuddin Tetrahedron Letters. 2000. 41, 7743
  • Synthesis and biological activity of new 4-amido and 4-sulphonamido analogoues of podophyllotoxin Ahmed Kamal, B. Ashwini Kumar, M. Arifuddin Bio-Org. Med. Chem. 2003, 11, 5135.
  • Ultrasonic activated efficient and facile method for the cleavage of epoxides with aromatic amines Ahmed Kamal, S. F. Adil and M. Arifuddin, Ultrasonics Sonochemistry, 2005, 12, 429-431.
  • Synthesis and Biological Activity of New 4β-N-Heteroaryl Analogues of Podophyllotoxin Ahmed Kamal, B. Ashwini Kumar, M. Arifuddin , Sunanda. G. Dastidar Letters in Drug Design & Discovery, 2006, 3, 3, 205-209

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