National Institute of Pharmaceutical Education and Research
Dept. of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Govt. of India NIPER HYDERABAD

CONTACT INFORMATION


Dr. M.V.Narendra Kumar Talluri,
Assistant Professor,
Department of Pharmaceutical Analysis,
NIPER-Hyderabad

BIOGRAPHY

Dr. M.V.N. Kumar Talluri is joined as a faculty member on 5th Aug.2009 at NIPER, Hyderabad. Previous positions held by him include Associate Scientific Manager at Biocon. He has a broad pharmaceutical experience in analytical activities in drug discovery, development and quality control, such as method development, specification design, regulatory documentation, etc. He received PhD degree (pharmaceutical analysis: impurity profiling of drugs and pharmaceuticals) from Indian Institute of Chemical Technology, Hyderabad. He has published ~50 articles in peer reviewed international research journals, invited articles/talks, presentations/abstracts in scientific conferences, book/ book chapters in his credit. He successfully supervised ~20 MS (Pharm) students for their research project works and presently guiding 5 MS and 2 PhD scholars. He is recipient of CSIR-Research fellowship, Institution of Chemists Associate ship awards. He has been in the EditorialAdvisoryBoard of Journal of Pharmaceutical science-clinical practice and serves as a reviewer for international journals of pharmaceutical analysis and his publications received good number of citations in various international journals. Science direct declared 4 times one of his article published in journal of pharmaceutical and biomedical analysis was among “Top 25 hottest articles. The Indian Drug Manufacturer’s Association conferred prestigious “Young Pharmaceutical Analyst Award 2011” for his outstanding research contribution in the field of Pharmaceutical Analysis.

AWARDS  &  QUALIFICATIONS
  • PhD from Indian Institute of Chemical Technology (CSIR)
  • Member Royal Society of Chemistry, 2013
  • IDMA-Young Pharmaceutical Analyst Award 2011 • Editorial Advisory Board member, Journal of Pharmaceutical science-clinical practice
  • Associate ship award of Institution of Chemists
  • Reviewer- Journal of Liquid Chromatography & Related Technologies, Current Pharmaceutical Analysis.. and Best presentation awards


RESEARCH SUMMARY

Drug impurity profiling, i.e. identification, structure elucidation and quantitative determination of impurities and degradation products in bulk drugs materials and pharmaceutical formulations is one of the most important fields of research activities. Development of stability indicating quantitative test methods, which can detect type and amount of degradation products over time. The use of such methods is to support a regulatory submission such as an Investigational New Drug Application, Drug Master File or an (A) NDA or generated to satisfy cGMP requirements. Bioanalysis: quantitative determination of drugs and their metabolites in biological fluids and the evaluation and interpretation of bioequivalence, pharmacokinetic studies. Metabolite identification and characterization studies by use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) etc. Standardization of herbal drugs: to obtain reliable chromatographic fingerprints that represent pharmacologically active and chemically characteristic components.

SOURCE OF FUNDING
  • Department of Pharmaceuticals (DOP), Ministry of chemical & fertilizers, Govt. of India


 

 


PUBLICATIONS
  • Development of a Validated Selective Stability-Indicating RP-HPLC Method: Identification and Characterization of major Stressed Degradation Products of Zotepine using LC-ESI-MS/Q-TOF. Journal of Pharmaceutical Analysis Х (2013).
  • Development of a molecularly imprinted polymer for selective extraction followed by zwitterionic hydrophilic interaction liquid chromatography (ZIC-HILIC) determination of 3-methylflavone-8-carboxylic acid, the main active metabolite of flavoxate in human urine. Journal of Separation Science 34 (2011).
  • Separation of sterioisomers of sertraline and its related enatiomeric impurities on a dimethylated β–Cyclodextrin stationary phase by HPLC. Journal of Pharmaceutical and Biomedical Analysis 50 (2009).
  •  LC-ESI-MS determination and pharmacokinetics of adrafinil in rats. Journal of Chromatography B 873 (2008).
  • Development of a validated RP-LC/ESI-MS-MS method for separation, identification and determination of related-substances of tamsulosin in bulk drugs and formulations. Journal of Pharmaceutical and Biomedical Analysis 46 (2008).
  • Continuous counter current extraction, isolation and determination of solanesol in Nicotiana tobacum L. by non-aqueous reversed phase high performance liquid Chromatography. Journal of Pharmaceutical and Biomedical Analysis 46 (2008).

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