Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...

1. Dhiman, V.; Patil, K.; Velip, L.; Talluri, M. K.; Gananadhamu, S. Comprehensive degradation profiling and influence of different oxidizing reagents on tinoridine hydrochloride: Structural characterization of its degradation products using HPLC and HRMS. Rapid Communications in Mass Spectrometry 2022, 36 (1), e9210. https://doi.org/10.1002/rcm.9210
2. Dhiman, V.; Singh, S.; Balhara, A.; Kushwah, B. S.; Velip, L.; Golla, V. M.; Samanthula, G. Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 208, 114459. https://doi.org/10.1016/j.jpba.2021.114459
3. Velip, L.; Dhiman, V.; Kushwah, B. S.; Golla, V. M.; Gananadhamu, S. Identification and characterization of urapidil stress degradation products by LC-Q-TOF-MS and NMR: Toxicity prediction of degradation products. Journal of Pharmaceutical and Biomedical Analysis 2022, 211, 114612. https://doi.org/10.1016/j.jpba.2022.114612
4. Kushwah, B. S.; Golla, V. M.; Dhiman, V.; Samanthula, G.. Forced degradation studies on axitinib and characterization of its degradation products by liquid chromatography-high resolution mass spectrometry and nuclear magnetic resonance spectroscopy along with its in silico toxicity assessment. Separation Science Plus 2022, 5 (8), 431–441. https://doi.org/10.1002/sscp.20220004
5. Kushwah, B. S.; Padhy, H. P.; Khemchandani, R.; Golla, V. M.; Kanchupalli, V. K.; Sonti, R.; Samanthula, G.. Structural characterization of novel hydrolytic and oxidative degradation products of acalabrutinib by LC-Q-TOF-MS, H/D exchange and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 221, 115077. https://doi.org/10.1016/j.jpba.2022.115077
6. Kushwah, B. S.; Velip, L. G.; Bharani, K. K.; Surya, P. V.; Sinha, S.; Khurana, A.; Kankarne, Y.; Banothu, A. K.; Gananadhamu, S. A sensitive method for determination of nimesulide and its hydroxy metabolite in milk using validated UPLC-MS method. Talanta Open 2022, 6, 100160. https://doi.org/10.1016/j.talo.2022.100160
7. Vambhurkar, G.; Amulya, E.; Sikder, A.; Shah, S.; Famta, P.; Khatri, D. K.; Singh, S. B.; Srivastava, S. Nanomedicine Based Potentially Transformative Strategies for Colon Targeting of Peptides: State-of-the-Art. Colloids and Surfaces B: Biointerfaces 2022, 219, 112816. https://doi.org/10.1016/j.colsurfb.2022.112816
8. Singh, G.; Pushpa, T. K.; Gupta, S. K.; Srivastava, S.; Khatri, D. K.; Singh, S. B. Perspective on Cav-1 for Its Potential as Newer Therapeutics for Parkinson’s Disease. CNS & Neurological Disorders - Drug Targets 2022, 22, 1429–1438. https://doi.org/10.2174/1871527321666220909150406
9. Kushwah, B. S.; Padhy, H. P.; Khemchandani, R.; Golla, V. M.; Kanchupalli, V. K.; Sonti, R.; Samanthula, G. Structural Characterization of Novel Hydrolytic and Oxidative Degradation Products of Acalabrutinib by LC-Q-TOF-MS, H/D Exchange and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 221, 115077. https://doi.org/10.1016/j.jpba.2022.115077
10. Gajula, S. N. R.; Nathani, T. N.; Patil, R. M.; Talari, S.; Sonti, R. Aldehyde Oxidase Mediated Drug Metabolism: An Underpredicted Obstacle in Drug Discovery and Development. Drug Metabolism Reviews 2022, 54, 427. https://doi.org/10.1080/03602532.2022.2144879
11. Dhurjad, P.; Dhalaram, C. S.; Ali, N.; Kumari, N.; Sonti, R. Metal-Organic Frameworks in Chiral Separation of Pharmaceuticals. Chirality 2022, 34, 1419–1436. https://doi.org/10.1002/chir.23499
12. Sahoo, S. K.; Gajula, S. N. R.; Ahmad, M. N.; Kaul, G.; Nanduri, S.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Bioevaluation of Quinoline-4-Carbonyl Derivatives of Piperazinyl-Benzothiazinones as Promising Antimycobacterial Agents. Archiv der Pharmazie 2022, 11, 2200168. https://doi.org/10.1002/ardp.202200168
13. Gajula, S. N. R.; Vora, S. A.; Dikundwar, A. G.; Sonti, R. In Vitro Drug Metabolism Studies Using Human Liver Microsomes. IntechOpen 2022. https://doi.org/10.5772/intechopen.108246
14. Anchi, P.; Chilvery, S.; Tekalkar, S.; Gajula, S. N. R.; Sonti, R.; Godugu, C. Nimbolide Loaded Sustained Release Microparticles as Single-Dose Formulations for Effective Management of Arthritis. Journal of Drug Delivery Science and Technology 2022, 75, 103638. https://doi.org/10.1016/j.jddst.2022.103638
15. Moi, S.; Shekh, S.; Reddy, K. K. A.; Dhurjad, P.; Sonti, R.; Gowd, K. H. Peptide Cysteine Thiols Act as Photostabilizer of Avobenzone through Stabilizing the Transition State of Keto-Enol Tautomerization. Photochemistry and Photobiology 2022. https://doi.org/10.1111/php.13691
16. Gajula, S. N. R.; Navin, N. T.; Talari, S.; Shende, C.; Sonti, R. Green Bioanalysis: An Innovative and Eco-Friendly Approach for Analyzing Drugs in Biological Matrices. Bioanalysis 2022, 12, 881. https://doi.org/10.4155/bio-2022-0095
17. Dandekar, M. P.; Palepu, M. S. K.; Satti, S.; Jaiswal, Y.; Singh, A. A.; Dash, S. P.; Gajula, S. N. R.; Sonti, R. Multi-Strain Probiotic Formulation Reverses Maternal Separation and Chronic Unpredictable Mild Stress-Generated Anxiety- and Depression-Like Phenotypes by Modulating Gut Microbiome–Brain Activity in Rats. ACS Chemical Neuroscience 2022, 13, 1948. https://doi.org/10.1021/acschemneuro.2c00143
18. Santosh, K. S.; Sarvan, M.; Siva, N. R. G.; Mohammad, N. A.; Grace, K.; Srinivas, N.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Identification of Nitrofuranylchalcone Tethered Benzoxazole-2-Amines as Potent Inhibitors of Drug Resistant Mycobacterium tuberculosis Demonstrating Bactericidal Efficacy. Bioorganic & Medicinal Chemistry 2022, 64, 116777. https://doi.org/10.1016/j.bmc.2022.116777
19. Grzesiek, S.; Paladini, J.; Habazettl, J.; Sonti, R. Imatinib Disassembles the Regulatory Core of Abelson Kinase by Binding to Its ATP Site and Not by Binding to Its Myristoyl Pocket. Magnetic Resonance 2022, 3, 1. https://doi.org/10.5194/mr-3-91-2022
20. Gaurav, P.; Shaik, M. G.; Swayamsiddha, K.; Sai, M. C.; Dannarm, S. R.; Jitendra, G.; Sonti, R.; Srinivas, N. SmI2-Mediated C-Alkylation of Ketones with Alcohols in Microwave Conditions: A Novel Route to Alkylated Ketones. Chemistry – An Asian Journal 2022, 17, 8. https://doi.org/10.1002/asia.202200041
21. Makhal, P. N.; Dannarm, S. R.; Shaikh, A. S.; Sonti, R.; Kaki, V. R. TBHP-Mediated Selenocyclization of N-Allylbenzamides/Benzthioamides via In-Situ Generation of “PhSeOH” Species. ChemistrySelect 2022, 7, 14. https://doi.org/10.1002/slct.202200933
22. Gaurav, P.; Shaik, M. G.; Swanand, V. J.; Preeti, R.; Swayamsiddha, K.; Mahesh, P. S.; Dannarm, S. R.; Sonti, R.; Srinivas, N. Cu(I)-Catalyzed Microwave-Assisted Multicomponent Reaction Towards Synthesis of Diverse Fluorescent Quinazolino[4,3-b]Quinazolin-8-Ones and Their Photophysical Study. ChemistrySelect 2022, 7, 14. https://doi.org/10.1002/slct.202200500
23. Dhurjad, P.; Dhavaliker, C.; Gupta, K.; Sonti, R. Exploring Drug Metabolism by the Gut Microbiota: Modes of Metabolism and Experimental Approaches. Drug Metabolism and Disposition 2022, 50, 224. https://doi.org/10.1124/dmd.121.000669
24. Makhal, P. N.; Dannarm, S. R.; Sonti, R.; Shaikh, A. S.; Kaki, V. R. TBHP-Mediated Selenocyclization of N-Allylbenzamides/Benzthioamides via In Situ Generation of “PhSeOH” Species. ChemistrySelect 2022, 7, e202200933.
25. Patra, S.; Makhal, P. N.; Jaryal, S.; More, N.; Kaki, V. R. Anthocyanins: Plant-Based Flavonoid Pigments with Diverse Biological Activities. International Journal of Plant Based Pharmaceuticals 2022, 2, 118–127.
26. Shaikh, A. S.; Kiranmai, G.; Devi, G. P.; Makhal, P. N.; Sigalapalli, D. K.; Tokala, R.; Kaki, V. R.; Shankaraiah, N.; Nagesh, N.; Babu, B. N.; Tangellamudi, N. D. Exploration of Mercaptoacetamide-Linked Pyrimidine-1,3,4-Oxadiazole Derivatives as DNA Intercalative Topo II Inhibitors: Cytotoxicity and Apoptosis Induction. Bioorganic & Medicinal Chemistry Letters 2022, 65, 128697.
27. Jhingran, S.; Laxmikeshav, K.; Mone, S.; Kaki, V. R.; Shankaraiah, N. The Syntheses and Medicinal Attributes of Phenanthrenes as Anticancer Agents: A Quinquennial Update. Current Medicinal Chemistry 2022, 29, 3530–3556.
28. Saifi, M. A.; Shaikh, A. S.; Kaki, V. R.; Godugu, C. Disulfiram Prevents Collagen Crosslinking and Inhibits Renal Fibrosis by Inhibiting Lysyl Oxidase Enzymes. Journal of Cellular Physiology 2022, 237, 2516–2527.
29. The Transition Metal Complexes of Fe(II), Ni(II) and Cu(II) Derived from Phthalazine-Based Ligands: Synthesis, Crystal Structures and Biological Activities. Journal of Molecular Structure 1247 (2022): 131293. Patil SS, Tadavi SK, Dikundwar A, and Bendre RS. https://doi.org/10.1016/j.molstruc.2021.131293
30. Applications of Raman Spectroscopy in Solvent Distillation and Exchange During Early-Phase Chemical Synthesis. Spectroscopy 37, no. 5 (2022): 28–39. Ramachandran R, Narayanam M, Wethman R, Jayaraman K, Dikundwar A, and Bhutani H. https://doi.org/10.56530/spectroscopy.cd1689c2
31. The Relevance of Experimental Charge Density Analysis in Unraveling Noncovalent Interactions in Molecular Crystals. Molecules 27, no. 12 (2022): 3690. Thomas SP, Dikundwar A, Sarkar S, Pavan MS, Pal R, Hathwar VR, and Row TNG. https://doi.org/10.3390/molecules27123690
32. Babu, C. K.; Shubhra; Ghouse, S. M.; Singh, P. K.; Khatri, D. K.; Nanduri, S.; Singh, S. B.; Madan, J. Luliconazole Topical Dermal Drug Delivery for Superficial Fungal Infections: Penetration Hurdles and Role of Functional Nanomaterials. Curr. Pharm. Des. 2022, 28(20), 1611–1620. https://doi.org/10.2174/1381612828666220623095743
33. Baliram Gaikwad, N.; Kumar Sahoo, S.; Ommi, O.; Naiyaz Ahmad, M.; Pathan, A.; Kaul, G.; Nanduri, S.; Dasgupta, A.; Chopra, S.; Madhavi Yaddanapudi, V. Identification of 1,3-Substituted Pyrazole-Based Carboxamide Derivatives as Potent Antitubercular Agents. ChemistrySelect 2022, 7(40), e202203333. https://doi.org/10.1002/slct.202203333
34. Sahoo, S. K.; Gajula, S. N.; Ahmad, M. N.; Kaul, G.; Nanduri, S.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Bioevaluation of quinoline-4-carbonyl derivatives of piperazinyl-benzothiazinones as promising antimycobacterial agents. Arch. Pharm. 2022, 355(11), 2200168. https://doi.org/10.1002/ardp.202200168
35. Sahoo, S. K.; Ommi, O.; Maddipatla, S.; Singh, P.; Ahmad, M. N.; Kaul, G.; Nanduri, S.; Dasgupta, A.; Chopra; Yaddanapudi, S. A.; V. M. Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents. Mol. Divers. 2022, 1–16. https://doi.org/10.1007/s11030-022-10543-0
36. Parupalli, R.; Akunuri, R.; Kaul, G.; Akhir, A.; Saxena, D.; Ghouse, S. M.; Yaddanapudi, V. M.; Nanduri, S.; C. S. S. Serendipitous identification of Phenylhydrazine derivatives as potent inhibitors of Carbapenem-resistant Acinetobacter baumannii. Future Med. Chem. 2022, 14(22), 1621–1634. https://doi.org/10.4155/fmc-2022-0156
37. Akunuri, R.; Unnissa, T.; Vadakattu, M.; Bujji, S.; Mahammad Ghouse, S.; Madhavi Yaddanapudi, V.; Chopra, S.; Nanduri, S. Bacterial Pyruvate Kinase: A New Potential Target to Combat Drug-Resistant Staphylococcus aureus Infections. ChemistrySelect 2022, 7(29), e202201403. https://doi.org/10.1002/slct.202201403
38. Imran, M.; Ahmad, M. N.; Dasgupta, A.; Rana, P.; Srinivas, N.; Chopra, S. Novel Approaches for the Treatment of Infections Due to Multidrug-Resistant Bacterial Pathogens. Future Med. Chem. 2022, 14(15), 1133–1148. https://doi.org/10.4155/fmc-2022-0029
39. Akunuri, R.; Unnissa, T.; Kaul, G.; Akhir, A.; Saxena, D.; Wajidali, M.; Veerareddy, V.; Yaddanapudi, V. M.; Chopra, S.; Nanduri, S. Synthesis and Antibacterial Evaluation of Rhodanine and Its Related Heterocyclic Compounds against S. Aureus and A. Baumannii. Chem. Biodivers. 2022, 19(7), e202200213. https://doi.org/10.1002/cbdv.202200213
40. Sahoo, S. K.; Maddipatla, S.; Gajula, S. N. R.; Ahmad, M. N.; Kaul, G.; Nanduri, S.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Identification of Nitrofuranylchalcone Tethered Benzoxazole-2-Amines as Potent Inhibitors of Drug Resistant Mycobacterium Tuberculosis Demonstrating Bactericidal Efficacy. Bioorg. Med. Chem. 2022, 64, 116777. https://doi.org/10.1016/j.bmc.2022.116777
41. Srikanth, D.; Joshi, S. V.; Shaik, M. G.; Pawar, G.; Bujji, S.; Kanchupalli, V.; Chopra, S.; Nanduri, S. A Comprehensive Review on Potential Therapeutic Inhibitors of Nosocomial Acinetobacter Baumannii Superbugs. Bioorg. Chem. 2022, 124, 105849. https://doi.org/10.1016/j.bioorg.2022.105849
42. Chinchilli, K. K.; Royyala, V. N.; Thacker, P. S.; Angeli, A.; Danaboina, S.; Singh, P.; Nanduri, S.; Supuran, C. T.; Arifuddin, M. Design, Synthesis, SAR, and Biological Evaluation of Saccharin-Based Hybrids as Carbonic Anhydrase Inhibitors. Arch. Pharm. 2022, 355(8), 2200019. https://doi.org/10.1002/ardp.202200019
43. Tamang, N.; Andrews, C.; Mavileti, S. K.; Nanduri, S.; Golakoti, N. R.; Karanam, B. Anti-Cancer Activity of Heteroaromatic Acetals of Andrographolide and Its Isomers. New J. Chem. 2022, 46(20), 9745–975. https://doi.org/10.1039/d2nj01055k
44. Pawar, G.; Mahammad Ghouse, S.; Kar, S.; Manohar Chelli, S.; Reddy Dannarm, S.; Gour, J.; Sonti, R.; Nanduri, S. SmI2-Mediated C-Alkylation of Ketones with Alcohols under Microwave Conditions: A Novel Route to Alkylated Ketones. Chem. Asian J. 2022, 17(8), e202200041. https://doi.org/10.1002/asia.202200041
45. Pawar, G.; Ghouse, S. M.; Joshi, S. V.; Rana, P.; Kar, S.; Sarma, P. M.; Dannarm, S. R.; Sonti, R.; Nanduri, S. Cu(I)-Catalyzed Microwave-Assisted Multicomponent Reaction Towards Synthesis of Diverse Fluorescent Quinazolino[4,3-b]Quinazolin-8-Ones and Their Photophysical Study. ChemistrySelect 2022, 7(14), e202200500. https://doi.org/10.1002/slct.202200500
46. Jyothi, S.; Ghouse, V. G. S.; Khatri, S. M.; Nanduri, S. K.; Singh, S.; Madan, S. B.; J. Lipid Nanoparticles in Topical Dermal Drug Delivery: Does Chemistry of Lipid Persuade Skin Penetration? J. Drug Deliv. Sci. Technol. 2022, 69, 103176. https://doi.org/10.1016/j.jddst.2022.103176
47. Akunuri; Vadakattu, R.; Kaul, M.; Akhir, G.; Saxena, A.; Ahmad, D.; Bujji, M. N.; Joshi, S.; Dasgupta, S. V.; Yaddanapudi, A.; Chopra, V. M.; Nanduri, S. Synthesis and Antibacterial Evaluation of 3,4-Dihydro-1H-Benzo[b]Azepine-2,5-Dione Derivatives. ChemistrySelect 2022, 7(7), e202104478. https://doi.org/10.1002/slct.202104478