Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...

1. Kumari, P.; Dhane, T. S.; Sathish, M.; Singitham, S.; Shankaraiah, N. Copper(II)-Mediated Regioselective ortho-C–N Bond Formation on Phthalazinones Employing Sulfonamides. ChemistrySelect 2026, 11, e73764. https://doi.org/10.1002/slct.73764
2. Dastari, S.; Shankaraiah, N. Therapeutic Potential of Spirocyclopropyl Oxindoles: Latest Developments in Drug Discovery. Future Medicinal Chemistry 2026, 18, 1753–1767. https://doi.org/10.1080/17568919.2026.2676782
3. Jha, A.; Dastari, S.; Sathish, M.; Shankaraiah, N. NIS-Mediated Olefination of Quinoxalin-2(1H)-ones Using Ketone Derivatives: A Facile Synthetic Access to (Z)-Enaminone Frameworks. Asian Journal of Organic Chemistry 2026, 15, e70463. https://doi.org/10.1002/ajoc.70463
4. Gupta, S.; Ezhilmathe, A.; Galla, M. S.; Godugu, C.; Shankaraiah, N. Copper(II)-Catalyzed One-Pot Synthesis of Thiazole/Benzothiazole-Based Isoquinolin-1(2H)-ones as Potential Cytotoxic and VEGFR-2 Inhibitors. Bioorganic Chemistry 2026, 170, 109506. https://doi.org/10.1016/j.bioorg.2026.109506
5. Singitham, S.; Galla, M. S.; Avvaru, S. J.; Sathish, M.; Kumari, P.; Dikundwar, A. G.; Shankaraiah, N. Visible-Light Mediated One-Pot Synthesis of Pyrazolo[3,4-b]Pyridines via Intramolecular Rearrangement. Asian Journal of Organic Chemistry 2025, 15, e70344. https://doi.org/10.1002/ajoc.70344
6. Kale, N. B.; Galla, M. S.; Shankaraiah, N. Harnessing Functionalized Alkynes in Annulation Reactions: A Comprehensive Review. Asian Journal of Organic Chemistry 2026, 15, e70290. https://doi.org/10.1002/ajoc.70290
7. Dastari, S.; Kopuri, S.; Jha, A.; Avvaru, S. J.; Dikundwar, A. G.; Shankaraiah, N. Metal-Free, Solvent-Controlled Divergent Synthesis of Substituted α-Keto Amides/Benzimidazoquinazolines: DFT, Crystallographic Analysis and in Silico Studies. Journal of Molecular Structure 2026, 1353, 144581. https://doi.org/10.1016/j.molstruc.2025.144581
8. Ramachandran, R. K.; Sasmal, A.; Dhiman, V.; Chaganti, S.; Jagtap, S.; Golla, V. M.; Samanthula, G. Steroidal Saponin Diversity in Costus speciosus Elucidated by Liquid Chromatography–Quadrupole Time-of-Flight Tandem Mass Spectrometry Coupled with Feature-Based Molecular Networking. Journal of Analytical Chemistry 2026, 81 (1), 115–126. https://doi.org/10.1134/S1061934825701436
9. Pimpre, K.; Chaganti, S.; Khemchandani, R.; Pilli, P.; Kommalapati, H.; Samanthula, G. Integrative Study on Triclabendazole Stability: Forced Degradation and In Silico Toxicity Prediction of Degradation Products. Biomedical Chromatography 2026, 40 (2), e70331. https://doi.org/10.1002/bmc.70331
10. Prasad, S. V.; Rahaman, S. A.; Samanthula, G.; Lankalapalli, S. P.; Pilli, P. Separation and Characterization of Degradation Impurities of Voxelotor by Liquid Chromatography and High Resolution Mass Spectrometry. Separation Science Plus 2026, 9 (2), e70192. https://doi.org/10.1002/sscp.70192
11. Shaikh, N.; Chaganti, S.; Khemchandani, R.; Harini, D.; Mouli, H. C.; Samanthula, G. Identification and Structural Characterization of Degradation Products of Tivozanib Using LC-Q-TOF-MS/MS and NMR: An In Silico Approach for Degradation and Toxicity Prediction. Rapid Communications in Mass Spectrometry 2026, 40 (3), e10167. https://doi.org/10.1002/rcm.10167
12. Harini, D.; Mouli, H. C.; Raman, P. K.; Singh, N.; Shreya, S.; Khemchandani, R.; Shaikh, N.; Godugu, C.; Samanthula, G. Phytoconstituents of Gmelina Arborea as Potential Breast Cancer Inhibitors: LC-MS/MS, Docking, MD Simulations, and In Vitro Evaluation. Chemistry & Biodiversity 2026, 23 (3), e01930. https://doi.org/10.1002/cbdv.202501930
13. Shaikh, N.; Khemchandani, R.; Shevatkar, J.; Samanthula, G. Characterization of forced degradation products of tyrosine kinase inhibitor apatinib mesylate by LC-MS/MS and NMR with in silico toxicity assessment. Journal of Pharmaceutical and Biomedical Analysis 2026, 117492. https://doi.org/10.1016/j.jpba.2026.117492
14. Pilli, P.; Golla, V. M.; Chaganti, S.; Barik, P.; Kommalapati, H. S.; Pimpre, K.; Samanthula, G. Comprehensive Forced Degradation Study of Pemigatinib and Structural Elucidation of Its Degradation Products Using Liquid Chromatography–High-Resolution Mass Spectrometry and Nuclear Magnetic Resonance. Separation Science Plus 2026, 9 (5), e70243. https://doi.org/10.1002/sscp.70243
15. Khemchandani, R.; Pardhi, E.; Jadhav, A.; Shaikh, N.; Bhale, N.; Pilli, P.; Pimpre, K.; Mouli, H. C.; Doijad, N.; Mehra, N. K. Mechanistic enhancement of oral bioavailability through a coamorphous apremilast-aceclofenac systems: integrated LC-MS/MS Bioanalysis, in vivo pharmacokinetics, and PBPK modeling. European Journal of Pharmaceutics and Biopharmaceutics 2026, 115099. https://doi.org/10.1016/j.ejpb.2026.115099
16. Kommalapati, H.; Chaganti, S.; Pilli, P.; Pimpre, K.; Samanthula, G. Simultaneous LC–MS/MS Determination of Primary Leachables from Pharma Receptacles: 2-Mercaptobenzothiazole and 1,3-Diphenylguanidine. Chromatographia 2026, 1–10. https://doi.org/10.1007/s10337-026-04494-z
17. Khemchandani, R.; Pardhi, E.; Faizan, A. M.; Devi, P.; Godugu, C.; Mehra, N. K.; Samanthula, G. Integrated analytical characterization and multiscale modeling of supramolecular interactions in lumefantrine-curcumin coamorphous systems with enhanced biopharmaceutical and anticancer performance. Talanta 2026, 130216. https://doi.org/10.1016/j.talanta.2026.130216
18. Varpe, P.; Dask, T. K.; Srivastava, S.; Nanduri, S. Investigating the Landscape of Personalized Medicine Approvals by the FDA. Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-026-10816-3
19. Gangawane, V. S.; Simran, S.; Kalokhe, V. M.; Musthafa, F.; Ahmad, A.; Godugu, C.; Srivastava, S. Gender Representation and Reporting in Post-Marketing Surveillance: A Review of FDA Regulatory Perspectives on Clinical Trials for Parkinson’s Disease. Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-026-10740-6
20. Mahajan, R.; Shah, S.; Srivastava, S.; Asthana, A.; Samanthula, G. Quality by Design-Assisted Separation and Characterization of Photolytic Degradation Products of Midostaurin Using UHPLC-Q-TOF-MS/MS: In-Silico Prediction and Toxicity Assessment. Rapid Communications in Mass Spectrometry 2026, 40. https://doi.org/10.1002/rcm.70120
21. Singh, A. K.; Kolipaka, T.; Pandey, G.; Wagh, S.; Samadder, B.; Srivastava, S. Harnessing Polysaccharide-Based Approaches for Posterior Ocular Disorders: Therapeutic Applications, Regulatory Perspectives, Challenges, and Future Directions. Journal of Drug Delivery Science and Technology 2026, 123, 108472. https://doi.org/10.1016/j.jddst.2026.108472
22. Devi, A.; Phatale, V.; Shukla, S.; Shetty, P.; Srivastava, A.; Chaure, P.; Khairnar, P.; Srivastava, S. From Oceanic Depths to Oncology Frontlines: Fucoidan as a Marine-Forged Bioactive Agent Targeting Non-Small Cell Lung Cancer. Food Bioscience 2026, 82, 109461. https://doi.org/10.1016/j.fbio.2026.109461
23. Sahane, P.; Khairnar, P.; Vambhurkar, G.; Phatale, V.; Kumar, R.; Srivastava, S. QbD-Guided Development and In Silico, In Vitro, Ex Vivo, and In Vivo Dermatokinetic Evaluation of a Fluvastatin-Loaded Transferosomal Hydrogel for the Management of Melanoma. Biomaterials Advances 2026, 188, 215046. https://doi.org/10.1016/j.bioadv.2026.215046
24. Hedaoo, A.; Khairnar, P.; Vambhurkar, G.; Sahane, P.; Kumar, R.; Sharma, A.; Sharma, A.; Srivastava, S. Quality by Design-Endorsed Nilotinib-Laden Liposomal Gel for Enhanced Dermal Delivery in Melanoma Management: Fabrication, Optimization, In Silico, In Vitro, and Ex Vivo Studies. ACS Applied Bio Materials 2026. https://doi.org/10.1021/acsabm.5c01778
25. Famta, P.; Vambhurkar, G.; Pandey, G.; Wagh, S.; Sharma, A.; Pandia, C.; Samadder, B.; Srivastava, S. Repurposing Statins for the Management of Head and Neck Squamous Cell Carcinoma: A Systematic Review of Preclinical and Clinical Evidence. Medical Oncology 2026, 43. https://doi.org/10.1007/s12032-026-03302-w
26. Amulya, E.; Kumari, D.; Kumar, R.; Vambhurkar, G.; Dandekar, M. P.; Srivastava, S. Nose-to-Brain Delivery of Riluzole-Loaded Nanoemulsion in a Controlled Cortical Impact-Induced Traumatic Brain Injury: Insights from In Vitro, Ex Vivo, and In Vivo Studies. Colloids and Surfaces B: Biointerfaces 2026, 267, 115955. https://doi.org/10.1016/j.colsurfb.2026.115955
27. Joga, R.; Vambhurkar, G.; Pilli, P.; Kumar, R.; Siragam, S.; Samanthula, G.; Srivastava, S. Regulatory Science-Aligned Development and Multivariate Optimisation of a Lidocaine-Laden Novel Nanoemulgel for the Topical Management of Imiquimod-Induced Psoriasis in BALB/c Mice. Journal of Drug Delivery Science and Technology 2026, 124, 108601. https://doi.org/10.1016/j.jddst.2026.108601
28. Sreya, R.; Nene, S.; Pathade, V.; Vambhurkar, G.; Phatale, V.; Srivastava, S. Ruxolitinib Phosphate-Laden Nanoemulgel: Amelioration of Ex Vivo Permeation and In Vivo Therapeutic Efficacy for the Effective Therapeutic Management of Psoriasis. Inflammopharmacology 2026. https://doi.org/10.1007/s10787-026-02286-3
29. Sikder, A.; Naresh Katarpawar, S.; Kumar, R.; Phatale, V.; Vambhurkar, G.; Pandey, G.; Wagh, S.; Sharma, A.; Amulya, E.; Khairnar, P.; Dikundwar, A. G.; Srivastava, S. QbD-Based Intranasal pH-Sensitive Ibrutinib Liposomes for Glioblastoma Management: In Vitro, Ex Vivo, and In Vivo Pharmacokinetics and Brain Distribution Assessment. European Journal of Pharmaceutics and Biopharmaceutics 2026, 225, 115121. https://doi.org/10.1016/j.ejpb.2026.115121
30. Simran, S.; Thakur, A.; Ahire, A. K.; Srivastava, S.; Asthana, A. Evaluating Regulatory Oversight through Major In Vitro Diagnostic Recalls: A Retrospective Study of FDA Data (2015–2024). Expert Review of Medical Devices 2026, 23, 723–731. https://doi.org/10.1080/17434440.2026.2669127
31. Shende, P.; Joga, R.; Yerram, S.; Gandhi, K.; Sowndharya, M.; Srivastava, S. Delving into the Regulations, Policies, Legislation, and Diversified Strategies across the US & Europe for Tackling Antimicrobial Resistance. Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-026-10486-1
32. Wagh, S.; Famta, P.; Shah, S.; Vambhurkar, G.; Kumar, R.; Sharma, A.; Pandey, G.; Singh, G.; Khairnar, P.; Sikder, A.; Sharma, A.; Shinde, S.; Pandia, C.; Samadder, B.; Kalia, N. P.; Srivastava, S. Quality by Design Manoeuvred Cabazitaxel-Loaded Polycaprolactone Nanoparticles for Management of Melanoma: Development, Optimization, In Silico Modeling and In Vitro Studies. Journal of Cluster Science 2026, 37. https://doi.org/10.1007/s10876-026-03026-x
33. Kaur, J.; Famta, P.; Srivastava, S.; Thakur, G.; Awasthi, A.; Singh, S. K. RNAi-Loaded Exosomes for the Management of Breast Cancer: Emerging Paradigms in Precision Therapy. Advanced Biology 2026, 10. https://doi.org/10.1002/adbi.70127
34. Gadekar, K. V.; Joga, R.; Yerram, S.; Waiker, S.; Srivastava, S. A Five-Year Trend Analysis of USFDA Expedited Approvals and Designations for New Drug Applications (2020–2024). Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-026-10399-z
35. Vijay, G. K.; Joga, R.; Yerram, S.; Waiker, S.; Gandhi, K.; M, S.; Srivastava, S. Psychedelics in Focus: Clinical Trial Advancements, USFDA Breakthrough Designations, Innovative Approaches, Legal and Regulatory Aspects. Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-026-10393-5
36. Kumari, G.; Kundu, S.; Famta, P.; Kalahasti, K. K.; Srivastava, S.; Reddy, G. B.; Srinivasarao, D. A. Core-Shell Nanotherapeutics for Diabetic Cataract and Retinopathy: Current State-of-the-Art and Translational Challenges. Drug Delivery and Translational Research 2026, 16, 1188–1221. https://doi.org/10.1007/s13346-025-01971-0
37. Devi, A.; Singh, S. B.; Srivastava, S.; Dandekar, M. P. Urolithin A Reverses Intranigral Rotenone-Generated Parkinsonism by Modulating DNA Methyltransferase 1 and α-Synuclein Axis in Rats. ACS Chemical Neuroscience 2026, 17, 1611–1629. https://doi.org/10.1021/acschemneuro.5c00362
38. Negi, M.; Amulya, E.; Phatale, V.; Kumar, R.; Srivastava, S. Nose-to-Brain Delivery of Berberine-Loaded Nanoemulsion: Amelioration of Brain Targeting, Behavioral, Pharmacokinetic, and Biodistribution Insights for Alzheimer’s Intervention. Biomaterials Advances 2026, 184, 214835. https://doi.org/10.1016/j.bioadv.2026.214835
39. Pandey, G.; Kolipaka, T.; Yadav, D.; Methri, S. M.; Singh, A. K.; Natesan, S.; Srivastava, S. Next-Generation Polymer-Based Nanofiber Ocular Inserts: Fabrication Innovations, Therapeutic Applications, Regulatory Perspectives, and Future Directions. International Journal of Pharmaceutics 2026, 695, 126781. https://doi.org/10.1016/j.ijpharm.2026.126781
40. Yerram, S.; Muhammad Nizam, V. P.; Srivastava, S.; Nanduri, S. Nitrosamine Contamination in Pharmaceuticals: A Retrospective Regulatory Analysis of USFDA Recalls and Risk Mitigation Strategies (2018–2025). Therapeutic Innovation & Regulatory Science 2026, 60, 519–533. https://doi.org/10.1007/s43441-025-00891-y
41. Patel, P. S.; Pandey, G.; Kumar, A.; Misra, S. K.; Roy, S.; Awasthi, A.; Wagh, S.; Srivastava, S.; Kapoor, A. 3D Bioprinting Employing Hydrogels for Tissue Engineering: Innovations, Challenges, and Regulatory Frontiers. Biomedical Materials & Devices 2026. https://doi.org/10.1007/s44174-026-00671-8
42. Abraham, N.; Pandey, G.; Kolipaka, T.; Kanaujiya, S.; Arya, D. K.; Kapoor, D. D.; Gupta, R. K.; Rajinikanth, P. S.; Srivastava, S. Multifunctional Bilayered Nanofibrous Scaffold of Chitosan/Poly(caprolactone) Enriched with Simvastatin and Thymoquinone for Accelerated Diabetic Wound Healing. International Journal of Biological Macromolecules 2026, 353, 151109. https://doi.org/10.1016/j.ijbiomac.2026.151109
43. Kolipaka, T.; Pandey, G.; Amulya, E.; Singh, A. K.; Srinivasarao, D. A.; Srivastava, S. Innovative siRNA Strategies: Scaling New Horizons in Diabetic Foot Ulcer Therapeutics. Bionanoscience 2026, 16. https://doi.org/10.1007/s12668-025-02389-1
44. Sowndharya, M.; Joga, R.; Yerram, S.; Gandhi, K.; Waiker, S.; Vijay, G. K.; Srivastava, S. Exploring the Role and Trends of USFDA’s Efficacy Supplement Approvals for NDA in Fulfilling Unmet Medical Needs in Healthcare (2019–2023). Journal of Pharmaceutical Innovation 2026, 21. https://doi.org/10.1007/s12247-025-10208-z
45. Shukla, S.; Phatale, V.; Khairnar, P.; Puri, N.; Sahane, P.; Wagh, S.; Sharma, A.; Srinivasarao, D. A.; Srivastava, S. Emerging Metallic Nanoparticle Modalities in Oral Squamous Cell Carcinoma: A Comprehensive Review on Theranostic Strategies and Future Perspectives. ACS Applied Bio Materials 2026, 9, 529–572. https://doi.org/10.1021/acsabm.5c01714
46. Jain, A.; Pandey, G.; Kolipaka, T.; Sharma, A.; Arya, D. K.; Rajinikanth, P. S.; Srivastava, S. Electrospun Poly(vinyl alcohol)/Zein-Based Nanofibrous Dressings Co-Loaded with Pramipexole and Hesperidin for Diabetic Wound Management: In Silico, In Vitro, and In Vivo Assessments. International Journal of Biological Macromolecules 2026, 340, 150092. https://doi.org/10.1016/j.ijbiomac.2026.150092
47. Kaur, J.; Famta, P.; Srivastava, S.; Awasthi, A.; Singh, T. G.; Pal, S.; Charu; Singh, S. K. Ginger Pharmacology from Tradition to Innovation: Modern Clinical Relevance and Nanotherapeutics. Journal of the Science of Food and Agriculture 2026, 106, 5751–5774. https://doi.org/10.1002/jsfa.70468
48. Bhale, N. A.; Subha Jahnavi, A.; Khemchandani, R.; Vambhurkar, G.; Suradkar, R. V.; Shah, S.; Patel, R.; Doijad, N. S.; Samanthula, G.; Srivastava, S.; Dikundwar, A. G. Drug–Drug Coamorphous System of Tadalafil and Finasteride for Enhanced Pharmaceutical Performance. Molecular Pharmaceutics 2026, 23, 127–138. https://doi.org/10.1021/acs.molpharmaceut.5c00513
49. Bhalerao, H. A.; Dhurjad, P.; Bharate, A.; Sonti, R. A Single Bioanalytical LC-MS/MS Method for the Quantification of Pelitinib Across Biological Matrices: An Insight into In Vitro Metabolic Stability and In Vivo Pharmacokinetics. Journal of Pharmaceutical and Biomedical Analysis 2026, 280, 117622. https://doi.org/10.1016/j.jpba.2026.117622
50. Yadav, R.; Chary, P. S.; Bhalerao, H. A.; Sonti, R.; Mehra, N. K. Development, Validation and Application of LC-MS/MS Method for Simultaneous Determination of Irinotecan and Cyclosporine in Co-Loaded Self-Nanoemulsifying Drug Delivery System. Annales Pharmaceutiques Françaises 2026. https://doi.org/10.1016/j.pharma.2026.05.007
51. Talari, S.; Nelwade, P. T.; Sonti, R. Isolation and Structural Characterisation of the Degradation Products of Tazemetostat Hydrobromide, an FDA-Approved EZH2 Inhibitor: Evidence for Two Distinct N-Oxidation Pathways. Journal of Molecular Structure 2026, 1366, 146071. https://doi.org/10.1016/j.molstruc.2026.146071
52. Dhannura, S.; Vijayasarathy, M.; Patil, K.; Manjunath, B.; Sonti, R.; Revanasiddappa, P. D.; Gowd, K. H. Site-Specific Post-Translational Modifications Regulate the Binding Affinity of Conus amadis α-Conotoxin Am2005 to Ac-AChBP. Journal of Biomolecular Structure and Dynamics 2026, 1–21. https://doi.org/10.1080/07391102.2026.2648676
53. Mukhopadhyay, N.; Satti, S.; Sen, S.; Kumar, A.; Sandbhor, R.; Dikundwar, A. G.; Kaki, V. R.; Dandekar, M. P. Elucidation of Potential Anti-Inflammatory Targets of Machilus macrantha (Gulmavu) by Utilizing GC–MS, Network Pharmacological Analysis, and Experimental Validation. Journal of Pharmaceutical Innovation 2026, 21, 173. https://doi.org/10.1007/s12247-026-10389-1
54. Mukhopadhyay, N.; Satti, S.; Sen, S.; Kumar, A.; Sandbhor, R.; Dikundwar, A. G.; Dandekar, M. P.; Kaki, V. R. Exploring the Potential Targets and Elucidating the Molecular Mechanisms Underlying the Anti-inflammatory Activity of Plectranthus amboinicus (Karpuravalli) in the Arachidonic Acid Metabolic Pathway by Network Pharmacology, Molecular Docking and Experimental Validation. Journal of Computational Biophysics and Chemistry 2026, 25 (11), 2325–2349.